793 By protecting against cutaneous inflammation, deep epidermal pigmentation provided additional advantages for ancestral humans
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Protection against LPS-induced cartilage inflammation and degradation provided by a biological extract of Mentha spicata
BACKGROUND A variety of mint [Mentha spicata] has been bred which over-expresses Rosmarinic acid (RA) by approximately 20-fold. RA has demonstrated significant anti-inflammatory activity in vitro and in small rodents; thus it was hypothesized that this plant would demonstrate significant anti-inflammatory activity in vitro. The objectives of this study were: a) to develop an in vitro extraction...
متن کاملCutaneous pigmentation after photosensitivity induced by vandetanib therapy.
BACKGROUND Photosensitivity has been reported in patients who were treated with vandetanib (ZD6474), an inhibitor of epidermal growth factor receptor, vascular endothelial growth factor receptor, and the RET (rearranged during transfection) kinases. OBSERVATIONS We describe the occurrence of cutaneous hyperpigmentation after photosensitivity in 2 patients who were treated with vandetanib. The...
متن کاملRationale for using multiple antioxidants in protecting humans against low doses of ionizing radiation.
Health risks of low doses of ionizing radiation (10 cGy or less) may not be accurately estimated in humans by epidemiological study or mathematical modelling because of several inherent confounding factors including environmental, dietary and biological variables that cannot be accounted for in any radio-epidemiological study. In addition, the expression of radiation-induced damage in humans no...
متن کاملEcosystem function and services provided by the deep sea
Introduction Conclusions References
متن کاملSegmental pigmentation disorder: A rare form of cutaneous dyspigmentation
Background: Segmental pigmentation disorder (SegPD) is a rare type of cutaneous dyspigmentation. This hereditary disorder, first described some 20 years ago, is characterized by hypo and hyperpigmented patches on the trunk, extremities and less likely on the face and neck. These lesions are considered as a type of checkerboard pattern. Case Presentation: Herein, we present a 26-year-old male...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.03.869